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Reservar ahoraYes. Restylane has been used safely by dermatologists y plastic surgeons worldwide since 1996. Because Restylane is non-animal-based and fully biocompatible, allergy testing is not required. Our Los Angeles Restylane is free of any potentially infectious substances. The most commonly reported side effects were temporary enrojecimiento, hinchazón, y moretones temporales. These effects typically resolve within two to three days.